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Search Results for " tricyclic antidepressant "

20

Compounds

Cat No. Product Name Synonyms Targets
T3086 Mesoridazine Besylate Mesoridazine benzenesulfonate,Serentil Dopamine Receptor , 5-HT Receptor
Mesoridazine Besylate (Serentil) is a piperidine neuroleptic drug belonging to the class of drugs called phenothiazines, used in the treatment of schizophrenia. It is a metabolite of thioridazine.
T4274 Melitracen hydrochloride Thymeol hydrochloride,Melixeran Dopamine Receptor , 5-HT Receptor
Melitracen hydrochloride (Thymeol hydrochloride) , an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression.
T1327 Nortriptyline hydrochloride Desitriptyline HCl,EN-7048 hydrochloride,Desmethylamitriptyline hydrochloride,ELF-101 hydrochloride Apoptosis , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Norepinephrine , Autophagy , Histamine Receptor , Drug Metabolite
Nortriptyline hydrochloride (ELF-101 hydrochloride) is a metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
T37015 Iprindole 5-HT Receptor
Iprindole, a tricyclic indole antidepressant, is a dual weak inhibitor of noradrenaline and 5-HT uptake [1].
T22240 Amitriptyline Sigma receptor , 5-HT Receptor , Norepinephrine , Histamine Receptor
Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties. Amitriptyline is widely used to treat depression and neuropathic pain.
T0172 Maprotiline hydrochloride Maprotiline HCl,Psymion,Deprilept,Ludiomil 5-HT Receptor , Adrenergic Receptor , AChR , Norepinephrine , Autophagy , Histamine Receptor
Maprotiline hydrochloride (Psymion) is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.
T12232 Nitroxazepine CIBA 2330Go Serotonin Transporter
Nitroxazepine (CIBA 2330Go) is a serotonin-norepinephrine reuptake inhibitor, and treatment depression. Nitroxazepine is a tricyclic antidepressant (TCA) for the research of depression
T0255 Clomipramine hydrochloride Clomipramine HCl,Anafranil Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine , GST
Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demeth...
T7941 Imipramine hydrochloride Imipramine (hydrochloride),Tofranil,G 22355,Imipramine HCl,Melipramine Serotonin Transporter
Imipramine hydrochloride (Imipramine HCl) is a first generation tricyclic antidepressant that acts primarily as an inhibitor of serotonin and norepinephrine transporters (Kds = 1.4 and 37 nM, respectively).Imipramine hyd...
T1045 Trimipramine maleate Surmontil maleate Dopamine Receptor , 5-HT Receptor , Antibacterial , Adrenergic Receptor , Norepinephrine , Histamine Receptor
Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Mal...
T0185 Escitalopram Seroplex,S-(+)-Citalopram,(S)-Citalopram Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor , AChR , Norepinephrine , Histamine Receptor
Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patien...
T1568 Amoxapine CL-67772 GlyT
Amoxapine (CL-67772) exerts its antidepressant effect by inhibiting the re-uptake of norepinephrine and, to a lesser degree, of serotonin, at adrenergic nerve endings and blocks the response of dopamine receptors to dopa...
T60330 Metapramine
Metapramine (19560 RP) is a tricyclic antidepressant[1]. Metapramine inhibits norepinephrine reuptake without affecting the reuptake of serotonin or dopamine [1] [2] [3]. Metapramine is a low-affinity antagonist of the N...
T0204 Protriptyline hydrochloride Protriptyline HCl 5-HT Receptor , AChE
Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochloride (Protriptyline HCl) blocks the re-uptake of norepineph...
T0678 Amitriptyline hydrochloride Amitriptyline HCl,Tryptizol,Domical,Annoyltin Trk receptor , Sigma receptor , 5-HT Receptor , Serotonin Transporter , Sodium Channel , Adrenergic Receptor , AChR , Norepinephrine , Histamine Receptor
Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities.
T21013 Clomipramine Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina 5-HT Receptor
Clomipramine (Clomicalm) is a tricyclic antidepressant (TCA). It is used for the treatment of the panic disorder, obsessive-compulsive disorder, major depressive disorder, and chronic pain. It may decrease the risk of su...
T15773 Lofepramine Gamanil,Amplit,Leo 640,Lopramine 5-HT Receptor , Norepinephrine
Lofepramine (Leo 640) is a potent tricyclic antidepressant that is extensively metabolized to desipramine. It inhibits the serotonin and norepinephrine transporters by inhibiting neurons with Kd values of 70 and 5.4 nM, ...
T0991 Desipramine hydrochloride NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020 Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor
Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-upt...
T68070 Fezolamine Norepinephrine
Fezolamine is a novel orally available non-tricyclic compound with antidepressant activity. It is three to two times more selective in blocking synaptosomal uptake of [3H]norepinephrine than uptake of [4H]3-hydroxytrypta...
T20017 Melitracen Melitracene
Melitracen is a tricyclic antidepressant.

Compounds

Mesoridazine Besylate
T3086
Synonym: Mesoridazine benzenesulfonate,Serentil
Target: Dopamine Receptor, 5-HT Receptor
Melitracen hydrochloride
T4274
Synonym: Thymeol hydrochloride,Melixeran
Target: Dopamine Receptor, 5-HT Receptor
Nortriptyline hydrochloride
T1327
Synonym: Desitriptyline HCl,EN-7048 hydrochloride,Desmethylamitriptyline hydrochloride,ELF-101 hydrochloride
Target: Apoptosis, Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, AChR, Norepinephrine, Autophagy, Histamine Receptor, Drug Metabolite
Iprindole
T37015
Synonym:
Target: 5-HT Receptor
Amitriptyline
T22240
Synonym:
Target: Sigma receptor, 5-HT Receptor, Norepinephrine, Histamine Receptor
Maprotiline hydrochloride
T0172
Synonym: Maprotiline HCl,Psymion,Deprilept,Ludiomil
Target: 5-HT Receptor, Adrenergic Receptor, AChR, Norepinephrine, Autophagy, Histamine Receptor
Nitroxazepine
T12232
Synonym: CIBA 2330Go
Target: Serotonin Transporter
Clomipramine hydrochloride
T0255
Synonym: Clomipramine HCl,Anafranil
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine, GST
Imipramine hydrochloride
T7941
Synonym: Imipramine (hydrochloride),Tofranil,G 22355,Imipramine HCl,Melipramine
Target: Serotonin Transporter
Trimipramine maleate
T1045
Synonym: Surmontil maleate
Target: Dopamine Receptor, 5-HT Receptor, Antibacterial, Adrenergic Receptor, Norepinephrine, Histamine Receptor
Escitalopram
T0185
Synonym: Seroplex,S-(+)-Citalopram,(S)-Citalopram
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor, AChR, Norepinephrine, Histamine Receptor
Amoxapine
T1568
Synonym: CL-67772
Target: GlyT
Metapramine
T60330
Synonym:
Target:
Protriptyline hydrochloride
T0204
Synonym: Protriptyline HCl
Target: 5-HT Receptor, AChE
Amitriptyline hydrochloride
T0678
Synonym: Amitriptyline HCl,Tryptizol,Domical,Annoyltin
Target: Trk receptor, Sigma receptor, 5-HT Receptor, Serotonin Transporter, Sodium Channel, Adrenergic Receptor, AChR, Norepinephrine, Histamine Receptor
Clomipramine
T21013
Synonym: Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina
Target: 5-HT Receptor
Lofepramine
T15773
Synonym: Gamanil,Amplit,Leo 640,Lopramine
Target: 5-HT Receptor, Norepinephrine
Desipramine hydrochloride
T0991
Synonym: NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor
Fezolamine
T68070
Synonym:
Target: Norepinephrine
Melitracen
T20017
Synonym: Melitracene
Target:
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TargetMol