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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3086 | Mesoridazine Besylate | Mesoridazine benzenesulfonate,Serentil | Dopamine Receptor , 5-HT Receptor |
Mesoridazine Besylate (Serentil) is a piperidine neuroleptic drug belonging to the class of drugs called phenothiazines, used in the treatment of schizophrenia. It is a metabolite of thioridazine. | |||
T4274 | Melitracen hydrochloride | Thymeol hydrochloride,Melixeran | Dopamine Receptor , 5-HT Receptor |
Melitracen hydrochloride (Thymeol hydrochloride) , an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression. | |||
T1327 | Nortriptyline hydrochloride | Desitriptyline HCl,EN-7048 hydrochloride,Desmethylamitriptyline hydrochloride,ELF-101 hydrochloride | Apoptosis , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Norepinephrine , Autophagy , Histamine Receptor , Drug Metabolite |
Nortriptyline hydrochloride (ELF-101 hydrochloride) is a metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions. | |||
T37015 | Iprindole | 5-HT Receptor | |
Iprindole, a tricyclic indole antidepressant, is a dual weak inhibitor of noradrenaline and 5-HT uptake [1]. | |||
T22240 | Amitriptyline | Sigma receptor , 5-HT Receptor , Norepinephrine , Histamine Receptor | |
Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties. Amitriptyline is widely used to treat depression and neuropathic pain. | |||
T0172 | Maprotiline hydrochloride | Maprotiline HCl,Psymion,Deprilept,Ludiomil | 5-HT Receptor , Adrenergic Receptor , AChR , Norepinephrine , Autophagy , Histamine Receptor |
Maprotiline hydrochloride (Psymion) is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use. | |||
T12232 | Nitroxazepine | CIBA 2330Go | Serotonin Transporter |
Nitroxazepine (CIBA 2330Go) is a serotonin-norepinephrine reuptake inhibitor, and treatment depression. Nitroxazepine is a tricyclic antidepressant (TCA) for the research of depression | |||
T0255 | Clomipramine hydrochloride | Clomipramine HCl,Anafranil | Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine , GST |
Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demeth... | |||
T7941 | Imipramine hydrochloride | Imipramine (hydrochloride),Tofranil,G 22355,Imipramine HCl,Melipramine | Serotonin Transporter |
Imipramine hydrochloride (Imipramine HCl) is a first generation tricyclic antidepressant that acts primarily as an inhibitor of serotonin and norepinephrine transporters (Kds = 1.4 and 37 nM, respectively).Imipramine hyd... | |||
T1045 | Trimipramine maleate | Surmontil maleate | Dopamine Receptor , 5-HT Receptor , Antibacterial , Adrenergic Receptor , Norepinephrine , Histamine Receptor |
Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Mal... | |||
T0185 | Escitalopram | Seroplex,S-(+)-Citalopram,(S)-Citalopram | Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor , AChR , Norepinephrine , Histamine Receptor |
Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patien... | |||
T1568 | Amoxapine | CL-67772 | GlyT |
Amoxapine (CL-67772) exerts its antidepressant effect by inhibiting the re-uptake of norepinephrine and, to a lesser degree, of serotonin, at adrenergic nerve endings and blocks the response of dopamine receptors to dopa... | |||
T60330 | Metapramine | ||
Metapramine (19560 RP) is a tricyclic antidepressant[1]. Metapramine inhibits norepinephrine reuptake without affecting the reuptake of serotonin or dopamine [1] [2] [3]. Metapramine is a low-affinity antagonist of the N... | |||
T0204 | Protriptyline hydrochloride | Protriptyline HCl | 5-HT Receptor , AChE |
Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochloride (Protriptyline HCl) blocks the re-uptake of norepineph... | |||
T0678 | Amitriptyline hydrochloride | Amitriptyline HCl,Tryptizol,Domical,Annoyltin | Trk receptor , Sigma receptor , 5-HT Receptor , Serotonin Transporter , Sodium Channel , Adrenergic Receptor , AChR , Norepinephrine , Histamine Receptor |
Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities. | |||
T21013 | Clomipramine | Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina | 5-HT Receptor |
Clomipramine (Clomicalm) is a tricyclic antidepressant (TCA). It is used for the treatment of the panic disorder, obsessive-compulsive disorder, major depressive disorder, and chronic pain. It may decrease the risk of su... | |||
T15773 | Lofepramine | Gamanil,Amplit,Leo 640,Lopramine | 5-HT Receptor , Norepinephrine |
Lofepramine (Leo 640) is a potent tricyclic antidepressant that is extensively metabolized to desipramine. It inhibits the serotonin and norepinephrine transporters by inhibiting neurons with Kd values of 70 and 5.4 nM, ... | |||
T0991 | Desipramine hydrochloride | NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020 | Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor |
Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-upt... | |||
T68070 | Fezolamine | Norepinephrine | |
Fezolamine is a novel orally available non-tricyclic compound with antidepressant activity. It is three to two times more selective in blocking synaptosomal uptake of [3H]norepinephrine than uptake of [4H]3-hydroxytrypta... | |||
T20017 | Melitracen | Melitracene | |
Melitracen is a tricyclic antidepressant. |